Department of Immunopathology
The Department of Immunopathology offers services for patients from the WCH, private specialists, general practitioners, other hospitals in South Australia and in some cases nationally.
The service covers the diagnosis of immunodeficiencies in childhood involving assessment of
Humoral immunity covers serum immunoglobulin, IgA, IgG and IgM, and IgG subclasses measurement.
The department evaluates numbers and proportions of leukocyte subpopulation, CD3, CD4, CD8, CD19 etc as part of lymphocyte functional responses. These include lymphoproliferation to mitogens and antigens and production of cytokines. Measurement of serum cytokine levels is also available.
Neutrophil function is evaluated by assessment of, chemotaxis, bactericidal and fungicidal activities, leukocyte iodination reaction and respiratory burst (chemiluminescence and NBT reduction).
A routine service for measurement of total haemolytic complement activity (CH50), and components C3, C4 is provided. A screen for all the other complement components is available upon consultation.
Allergy testing includes total IgE, RAST allergen specific IgE antibodies to a wide range of allergens and IgG blocking antibody to bee venom.
Lymphocyte function, neutrophil function tests and special complement components require direct consultation.
How to access the service
An appropriate sample should be submitted with a completed pathology request form.
OR Immunology Secretary email@example.com
5th floor, Reiger Building
Ph (08) 8161 7216
Fax (08) 8161 6046